The Knights of the white cross The Order of Knights Hospitallers-or Knights of St John-originated in the times of the Crusades in 1119, though the foundation of a hospital for pilgrims in Jerusalem can be dated to 600 AD. It rose to be one of the most powerful Christian groups in the Holy Land. Its actions against Muslim forces were legendary but eventually Islam drove Christianity out and the order retreated to Cyprus. In 1309 Rhodes was subdued and became the order's new home. Battles with Barbary Corsairs and the Ottoman Turks followed culminating in the great siege and defeat at Rhodes by Suleiman in 1522. Malta then became the headquarters and it too withstood a gruelling assault in 1565. Further action included a decisive sea victory against the Corsairs at Lepanto and this history concludes with the siege of Vienna as the Knights came to the end of their real influence and military power.