Science has the potential to do much good. But it can also be misused and cause harm. How can researchers become aware of the risks and share their insights responsibly? This volume gathers a premier group of scholars and practitioners to address cutting-edge dilemmas of "responsible policy engagement." The authors reflect on their own experiences and provide guidance on how to constructively communicate with policymakers - while also being transparent about the uncertainty and subtleties of the research process. The case studies cover tricky policy engagements on topics ranging from post-conflict power-sharing, atrocities prevention, NATO enlargement, economic crises, business and human rights, counterinsurgency and state-building, census data and polling, and intelligence analysis. To avoid pitfalls, the analyses offer a mix of ethical principles and practical advice, including setting cautionary ethical redlines, reflecting on one's position and values, and describing areas of consensus and degrees of uncertainty. Speaking Science to Power uncovers the temptations scholars may face to share particular results, overgeneralize findings, conceal uncertainty, or curry favor with policymakers, and then urges them to act responsibly. Epstein and Kaplan have collected incredibly valuable perspectives on the seemingly contradictory demands of science and democracy. The book provides insight into the complexities of responsible policy engagement and will be of great value to any expert jumping into the fray of policy and politics. I plan to use it in my graduate seminars on science policy. Highly recommended.