This field of Black girls' and women's health (BGWH) science is both transdisciplinary and interdisciplinary. As such, the contributors to this edited collection offer a unique lens to BGWH science, expanding our collective scientific worldviews. The contributing authors draw upon their ontological and epistemological knowledge to formulate pathways and inform methodologies for doing research and praxis to address BGWH. Each contributor draws upon these knowledges and offers the reader a way to better understand how their framing and writing can create change in the health of Black girls and women.